Asbestosis: Materials and Methods

bronchoalveolar lavageProteins present in bronchoalveolar lavage (BAL) fluid have been the object of study in recent years, both in normal subjects and in a variety of pulmonary diseases. Albumin, immunoglobulin G (IgG), and immunoglobulin A (IgA) are found in BAL fluid in normal subjects, but immunoglobulin M is rarely detected. Increases in all three classes of immunoglobulins have been described in various interstitial pulmonary diseases. These may originate from the intravascular space, reaching the lower respiratory tract by a process of transudation across the endothelial and pulmonary epithelial membranes or from local synthesis.

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